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Volume 349:815 August 21, 2003 Number 8
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Enfuvirtide for Prophylaxis against HIV Infection

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 by Kilby, J. M.
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To the Editor: In their review article on a new class of drugs that inhibit human immunodeficiency virus type 1 (HIV-1) fusion, Kilby and Eron (May 29 issue)1 underline the virologic and immunologic benefit of enfuvirtide for drug-resistant HIV-1 infection. In our opinion, this new compound also deserves attention for antiretroviral prophylaxis because it acts before the virus enters the cell, it has activity against resistant strains of HIV when the source of infection is a patient with resistance to multiple anti-HIV drugs, and its subcutaneous route of administration may immediately ensure effective serum levels. The use of enfuvirtide in . . . [Full Text of this Article]


Related Letters:

Enfuvirtide for Prophylaxis against HIV Infection
Cuzin L., Alvarez M., Ferranti S., Menichetti F.
Extract | Full Text | PDF  
N Engl J Med 2003; 349:2169-2170, Nov 27, 2003. Correspondence

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