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Previous Volume 350:80-82 January 1, 2004 Number 1 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In the Clinical Practice article about early Alzheimer's disease, Dr. Kawas (Sept. 11 issue)¹ discusses testing for reversible causes of dementia. More than 15 years ago, it was conclusively shown that true reversibility of dementia, especially in the elderly, was extremely rare.^2,3 More recent work has confirmed these findings, revealing improvement in less than 1 percent of cases.⁴

On the basis of the evidence, one should be quite conservative, and decisions about testing should be directed primarily by the clinical clues available from the history and physical examination. Kawas cites the American Academy of Neurology's universal neuroimaging . . . [Full Text of this Article]

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