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Correspondence
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Volume 350:87-88 January 1, 2004 Number 1
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More on Pseudohypocalcemia and Gadolinium-Enhanced MRI

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To the Editor: In their letter to the editor, Doorenbos et al. (Aug. 21 issue)1 describe seven cases of severe pseudohypocalcemia after gadolinium-enhanced magnetic resonance angiography with the use of gadodiamide. Their report represents an important warning to all physicians, especially since such laboratory interference can occur after any gadodiamide-enhanced magnetic resonance imaging (MRI) examination. Gadodiamide and gadoversetamide are the two gadolinium chelates known to interfere with the colorimetric methods of measuring serum calcium used in most hospitals.2,3,4,5 However, five other gadolinium contrast agents do not show this interference: gadopentetate dimeglumine (Magnevist) and gadoteridol (ProHance), which are widely used in . . . [Full Text of this Article]


Related Letters:

Severe Pseudohypocalcemia after Gadolinium-Enhanced Magnetic Resonance Angiography
Doorenbos C. J., Ozyilmaz A., van Wijnen M.
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N Engl J Med 2003; 349:817-818, Aug 21, 2003. Correspondence

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