Gout is the only enemy that I do not wish to have at my feet.
Reverend Sydney Smith, 1841
Gout, a disease that has been known since antiquity, is an acute,often recurrent arthritis mediated by the crystallization ofuric acid within the joints and typically associated with hyperuricemia.Described by Hippocrates during the Golden Age of Greece, goutwas originally a disease of the affluent, primarily observedin middle-aged men of the wealthy upper class ("the Patricianmalady"). A "disease of kings and king of diseases," gout hasoften kept good company, afflicting kings (including Alexanderthe Great, . . . [Full Text of this Article]
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From the Division of Nephrology, Hypertension, and Transplantation, University of Florida, Gainesville (R.J.J.); and the Center for Reproduction of Endangered Species, Zoological Society of San Diego, San Diego, Calif. (B.A.R.).
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