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Previous Volume 350:1073-1075 March 11, 2004 Number 11 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Migraine is a chronic disease that affects 12 percent of the general population. In addition to severe, debilitating headache, patients with migraines may experience nausea, vomiting, and sensitivity to light and sound. Migraine remains one of the most underdiagnosed and undertreated neurologic conditions and has substantial socioeconomic effects in developed countries. It is now considered to be a neurovascular disorder because its pathology involves important interactions between the cerebral nerves and blood vessels.

Current theories propose that migraine-specific triggers promote primary brain dysfunction, which evokes changes in the dilation of meningeal blood vessels and the activation of perivascular trigeminal nerves. . . . [Full Text of this Article]

Source Information

From the Department of Biology, Southwest Missouri State University, Springfield.

This article has been cited by other articles:

• Zhang, Z., Winborn, C. S., Marquez de Prado, B., Russo, A. F. (2007). Sensitization of Calcitonin Gene-Related Peptide Receptors by Receptor Activity-Modifying Protein-1 in the Trigeminal Ganglion. J. Neurosci. 27: 2693-2703 [Abstract] [Full Text]  
• Peroutka, S. J. (2005). NEUROGENIC INFLAMMATION AND MIGRAINE: IMPLICATIONS FOR THE THERAPEUTICS. Mol. Interv. 5: 304-311 [Abstract] [Full Text]