FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 350:1254-1256 March 18, 2004 Number 12 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by Nankivell, B. J. PubMed Citation

To the Editor: Nankivell et al. (Dec. 11 issue)¹ report that serial renal biopsies in recipients of kidney and pancreas transplants who were given calcineurin inhibitors showed that chronic rejection was rare but that, over time, these drugs led to irreversible lesions. The authors conclude that calcineurin inhibitors are unsuitable for long-term immunosuppression.

The authors should be congratulated for their informative contribution, but their conclusions may be challenged. With a regimen based on calcineurin inhibitors, Nankivell et al. report that the survival rate for kidney grafts, with data censored for patients who died, was 95.2 percent at 10 years. I . . . [Full Text of this Article]

HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  HELP  |  beta.nejm.org Comments and questions? Please contact us. The New England Journal of Medicine is owned, published, and copyrighted © 2008 Massachusetts Medical Society. All rights reserved.