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Correspondence
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Volume 350:1464-1466 April 1, 2004 Number 14
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DKK1 in Multiple Myeloma

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 by Tian, E.
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To the Editor: The color image accompanying the editors' summary of the article by Tian et al. (Dec. 25 issue)1 provides information that would be helpful in any future study on dickkopf 1 (DKK1) gene expression in multiple myeloma. The image is a whole-body 18F-fluorodeoxyglucose (18F-FDG) positron-emission tomographic (PET) scan with extensive evidence of marrow involvement; more than 60 lesions are identified. PET has been shown to be a sensitive indicator of disease in multiple myeloma2; in another study,3 71 bone lesions not seen on plain-film radiography were detected in 14 of 41 patients with multiple . . . [Full Text of this Article]




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