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Correspondence
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Volume 350:1575-1576 April 8, 2004 Number 15
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Oral Sucrose and Exercise Tolerance in McArdle's Disease

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by Vissing, J.
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To the Editor: Vissing and Haller (Dec. 25 issue)1 show that sucrose ingestion before exercise can markedly improve aerobic exercise tolerance in patients with McArdle's disease. However, as the authors note, this strategy may lead to increased insulin secretion that could potentially inhibit the use of fatty acids and is not useful in situations involving unexpected aerobic activity or prolonged physical activity. The authors may wish to consider uncooked cornstarch as a carbohydrate source for patients with McArdle's disease, as previously reported by Chen et al. in patients with type I glycogen storage disease.2 Bolus uncooked-cornstarch ingestion provides for a . . . [Full Text of this Article]



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