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Correspondence
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Volume 350:1576-1577 April 8, 2004 Number 15
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Acute Infectious Diarrhea

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by Thielman, N. M.
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To the Editor: In the article on acute infectious diarrhea by Thielman and Guerrant (Jan. 1 issue),1 we did not find any information on the role of probiotics. Treatment of acute infectious diarrhea is probably the main application of probiotic therapy in clinical practice. Lactobacilli are considered model probiotics, since they can augment innate and adaptive immune responses and stimulate the production of antiinflammatory interleukins.2 Clinical studies have shown that Lactobacillus rhamnosus GG (LGG) reduces the duration of acute infectious diarrhea induced by rotavirus.3 LGG has also significantly reduced the rate of occurrence of antibiotic-related diarrhea in adults.4 Furthermore, LGG . . . [Full Text of this Article]



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