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Case Records of the Massachusetts General Hospital
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Volume 350:166-176 January 8, 2004 Number 2
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Case 1-2004 — A 49-Year-Old Woman with Asymmetric Painful Neuropathy
David A. Chad, M.D., and E. Tessa Hedley-Whyte, M.D.

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Presentation of Case

A 49-year-old left-handed woman was evaluated in the neurology clinic because of painful asymmetric neuropathy.

The patient had been well until several years earlier, when numbness developed in the right hand. A right carpal-tunnel–release operation had been performed eight months before the current evaluation, but without benefit. During the four months before the evaluation, she experienced increasing burning pain in the same hand, and similar symptoms developed in the left hand. She frequently observed blisters on the first, second, and third digits of the right hand, without any recollection of injury. She had decreased sensation in the legs, particularly a . . . [Full Text of this Article]

Differential Diagnosis

Characterizing a Peripheral Neuropathy

The Process of Differential Diagnosis

Narrowing the Differential Diagnosis

Clinical Diagnosis

Dr. David A. Chad's Diagnosis

Pathological Discussion

Anatomical Diagnosis

Addendum


Source Information

From the Department of Neurology, UMass Memorial Health Care, and the Departments of Neurology and Pathology, University of Massachusetts Medical School, Worcester (D.A.C.); and the Department of Pathology, Division of Neuropathology, Massachusetts General Hospital, and the Department of Pathology, Harvard Medical School (E.T.H.-W.).


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