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Previous Volume 350:2181-2189 May 20, 2004 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Presentation of Case

A 76-year-old woman was referred to the Pain Center of this hospital because of pain and numbness in her feet and legs. Six years earlier, intermittent numbness had developed in the toes of her right foot; the numbness slowly spread to both feet and then to the lower legs. The pain was worse at night and awakened her with a burning sensation that involved both legs nearly up to the knees and extended at times to the hips. She rated her pain as 6 on a scale of 1 to 10, with 10 indicating the most intense pain. Additional symptoms . . . [Full Text of this Article]

Differential Diagnosis

Causes of Small-Fiber Neuropathies

Idiopathic Small-Fiber Neuropathy

Clinical Diagnosis

Dr. Anthony A. Amato's Diagnosis

Pathological Discussion

Discussion of Management

Anatomical Diagnosis

Source Information

From the Department of Neurology, Division of Neuromuscular Medicine, Brigham and Women's Hospital (A.A.A.); the Department of Neurology, Harvard Medical School (A.A.A., A.L.O.); and the Nerve Injury Unit, Departments of Anesthesia and Critical Care, and the Departments of Neurology and Neuropathology, Massachusetts General Hospital (A.L.O.) — all in Boston.

This article has been cited by other articles:

• Paticoff, J., Valovska, A., Nedeljkovic, S. S., Oaklander, A. L. (2007). Defining a Treatable Cause of Erythromelalgia: Acute Adolescent Autoimmune Small-Fiber Axonopathy. Anesth. Analg. 104: 438-441 [Abstract] [Full Text]  
• Oaklander, A. (2005). Erythromelalgia: Small-Fiber Neuropathy by Any Other Name?. Pediatrics 116: 293-294 [Full Text]