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Volume 350:2416-2417 June 3, 2004 Number 23
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B-Type Natriuretic Peptide in the Evaluation of Acute Dyspnea

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 by Mueller, C.
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To the Editor: Mueller et al. (Feb. 12 issue)1 conclude that rapid measurement of B-type natriuretic peptide in the emergency department improved the evaluation and treatment of patients with acute dyspnea. The authors state that echocardiography was "strongly recommended." However, they provide no data regarding left ventricular ejection fraction. About half of all patients with heart failure have preserved left ventricular systolic function,2 and there are important limitations in the use of B-type natriuretic peptide to diagnose heart failure with preserved systolic function, with considerable overlap in B-type natriuretic peptide levels in patients who have heart failure with preserved systolic . . . [Full Text of this Article]


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