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A correction has been published: N Engl J Med 2004;351(4):408.

Review Article
Medical Progress
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Volume 350:2487-2498 June 10, 2004 Number 24
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Pneumocystis Pneumonia
Charles F. Thomas, Jr., M.D., and Andrew H. Limper, M.D.

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Pneumocystis pneumonia remains the most prevalent opportunistic infection in patients infected with the human immunodeficiency virus (HIV).1,2 First identified as a protozoan nearly 100 years ago and reclassified as a fungus in 1988, pneumocystis cannot be propagated in culture.3,4,5,6 Few treatment options exist for patients with pneumocystis pneumonia. The number of patients who are receiving chronic immunosuppressive medication or who have an altered immune system and are thus at risk for pneumocystis pneumonia is rapidly growing.2 Although the prevalence of the acquired immunodeficiency syndrome (AIDS) has decreased in the Western hemisphere owing to the routine use of highly active antiretroviral . . . [Full Text of this Article]

Clinical Features of Pneumocystis Pneumonia

Diagnosis of Pneumocystis Infection

Prophylaxis and Treatment of Pneumocystis Pneumonia

Epidemiologic Features of Pneumocystis Pneumonia

The Biology of the Parasite

Host Response to Pneumocystis Infection

Lymphocyte Responses to Pneumocystis

Macrophages in Host Defense against Pneumocystis

Cytokine and Chemokine Networks

Alveolar Epithelial Cells and Proteins

Summary


Source Information

From the Thoracic Diseases Research Unit, Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine (C.F.T., A.H.L.), and the Department of Biochemistry and Molecular Biology (A.H.L.), Mayo Clinic College of Medicine, Rochester, Minn.

Address reprint requests to Dr. Limper at 8-24 Stabile Bldg., Mayo Clinic, Rochester, MN 55905, or at limper.andrew@mayo.edu.


Related Letters:

Pneumocystis Pneumonia
del Rio C., Barragan M., Franco-Paredes C., Udwadia Z. F., Doshi A. V., Bhaduri A. S., van Well G., van Furth M.
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N Engl J Med 2004; 351:1262-1263, Sep 16, 2004. Correspondence

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