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A 26-year-old man presented with blisters and erosions that had developed on his tongue over a 48-hour period (Panel A). The blisters had appeared primarily in his mouth, but several had also appeared on his face and trunk. There was no involvement of his eyes. The major complication has been laryngeal scarring due to blister formation.
Two years before this presentation, a biopsy showed an infiltrate of eosinophils in a subepidermal blister. Direct immunofluorescence of the biopsy specimen showed a linear deposition of IgG on the basement membrane. These findings were consistent with a diagnosis of cicatricial pemphigoid. On indirect . . . [Full Text of this Article] |
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