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Previous Volume 350:2542-2544 June 17, 2004 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The regulation of body weight adheres to the principles of thermodynamics: a positive energy balance causes weight gain, and weight loss occurs when the energy expenditure exceeds intake. More than half the adults in the United States are overweight or obese, and many of these people make an effort, at least intermittently, to lose weight. The results of clinical trials such as the Diabetes Prevention Program provide good evidence that a moderate amount of weight loss plus increased physical activity reduces the likelihood of progression from impaired glucose tolerance to type 2 diabetes mellitus.¹ Although the long-term health benefits of . . . [Full Text of this Article]

Source Information

From the Obesity and Nutrition Research Center, University of Pittsburgh Medical Center, Pittsburgh.

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