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A 12-year-old boy with acute myelogenous leukemia that had been diagnosed two months earlier presented to a hospital with fever and leg pain. He had received intravenous cytarabine two weeks earlier. He was pancytopenic, with a total leukocyte count of 1900 per cubic millimeter, a hemoglobin level of 6.8 g per deciliter, and a platelet count of 24,000 per cubic millimeter. The absolute granulocyte count was 190 per cubic millimeter. He was afebrile and had painful, ecchymotic areas on his legs that progressed with marked swelling during the next few hours. He was treated with ceftazidime and analgesics and was . . . [Full Text of this Article] |