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Volume 350:2617-2618 June 17, 2004 Number 25
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GB Virus C and Survival in Persons with HIV Infection

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by Williams, C. F.
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To the Editor: Williams et al. (March 4 issue)1 propose that GB virus C (GBV-C) interferes with the progression of human immunodeficiency virus (HIV) infection. Previous cross-sectional studies have shown that HIV-infected patients with GBV-C viremia have increased rates of survival.2,3,4 Williams et al. found no survival benefit associated with GBV-C viremia 12 to 18 months after HIV seroconversion but did observe that GBV-C viremia 5 to 6 years after HIV seroconversion was associated with a survival benefit.

In a similar, longitudinal study,5 we determined the GBV-C status both in the earliest available serum sample after the diagnosis of HIV . . . [Full Text of this Article]



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