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Correspondence
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Volume 350:2622 June 17, 2004 Number 25
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Polycystic Kidney Disease

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 by Wilson, P. D.
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To the Editor: According to Table 1 in Wilson's review of polycystic kidney disease (Jan. 8 issue),1 the MCKD2 gene has not been identified when, in fact, it has, and a genetic test is currently available. MCKD2 involves the mutation of a common urinary protein (Tamm–Horsfall protein), the function of which is unknown.2 This disease appears to be an example of an endoplasmic-reticulum storage disease.


Anthony J. Bleyer, M.D.
Wake Forest University School of Medicine
Winston-Salem, NC 27157
ableyer@wfubmc.edu


Thomas C. Hart, D.D.S., Ph.D.
National Institute of Dental and Craniofacial Research
Bethesda, MD 20892

Editor's note: The authors are parties . . . [Full Text of this Article]




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