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Volume 350:323-324 January 22, 2004 Number 4 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Sexual reproduction requires three types of differentiation: gonadal for the production of gametes, genital for the conveyance of gametes to a point of fertilization, and behavioral for the urge to behave sexually. Two articles in this issue of the Journal illuminate several of these steps.

MacLaughlin and Donahoe (pages 367–378) provide a current view of the genetics of gonadal development, describing genes that are responsible for the formation of the urogenital ridge and the migration of germ cells to it, resulting in the formation of a bipotential gonad (see Figure). Defects in the genes that are involved in this . . . [Full Text of this Article]

Source Information

From Harvard Medical School, Boston.

Related Letters:

Sex Determination, Differentiation, and Identity
Berenbaum S. A., Sandberg D. E., Baratz A. B., Migeon C. J., Berkovitz G. D., Wisniewski A. B., Tomasi P. A., Reiner W. G., Gearhart J. P., Donahoe P. K., MacLaughlin D. T.
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N Engl J Med 2004; 350:2204-2206, May 20, 2004. Correspondence

This article has been cited by other articles:

• Berenbaum, S. A., Sandberg, D. E., Baratz, A. B., Migeon, C. J., Berkovitz, G. D., Wisniewski, A. B., Tomasi, P. A., Reiner, W. G., Gearhart, J. P., Donahoe, P. K., MacLaughlin, D. T. (2004). Sex Determination, Differentiation, and Identity. NEJM 350: 2204-2206 [Full Text]