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Original Article
Brief Report
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Volume 350:361-366 January 22, 2004 Number 4
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Tanapox Infection in a College Student
A. Damian Dhar, M.D., Andrew E. Werchniak, M.D., Yu Li, Ph.D., Jeoffry B. Brennick, M.D., Cynthia S. Goldsmith, M.S., Richard Kline, M.S., Inger Damon, M.D., Ph.D., and Sidney N. Klaus, M.D.

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 by Frey, S. E.

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Tanapox infection is a poxvirus infection that is endemic to equatorial Africa. It begins with a febrile prodrome that is soon followed by the eruption of one or more large, superficial nodules, typically on the extremities. Complete recovery after several weeks is the rule, and there are no known permanent sequelae other than a scar at the site of infection. Although the disease is not uncommon in certain parts of Africa, only four previous cases have been reported in the United States. We describe a college student who acquired the disease while working with orphaned chimpanzees in Africa. We also . . . [Full Text of this Article]

Case Report

Methods

DNA Extraction

PCR

            Yatapoxvirus–Tanapox 2L Gene

            Yatapoxvirus–Tanapox 332-bp Amplicon from Pst 1 L Fragment

            Multiplex PCR Orthopoxvirus Assay (E9L)

Results

Discussion


Source Information

From the Department of Medicine, Section of Dermatology (A.D.D., A.E.W., S.N.K.), and the Department of Pathology (J.B.B.), Dartmouth Medical School, Hanover, N.H., and Dartmouth–Hitchcock Medical Center, Lebanon, N.H.; and the Centers for Disease Control and Prevention, Atlanta (Y.L., C.S.G., R.K., I.D.).

Address reprint requests to Dr. Klaus at the Department of Medicine, Section of Dermatology, Dartmouth–Hitchcock Medical Center, 1 Medical Center Dr., Lebanon, NH 03756.


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