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A correction has been published: N Engl J Med 2004;350(26):2726.

Clinical Practice
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Volume 350:476-481 January 29, 2004 Number 5
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Prevention of Hepatitis A with the Hepatitis A Vaccine
Allen S. Craig, M.D., and William Schaffner, M.D.

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 by Acheson, D. W.K.
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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations.

A 34-year-old man presented to the emergency department two weeks after returning from a trip to India, reporting a six-day history of anorexia, vomiting, malaise, fatigue, and dark urine. His alanine aminotransferase level was 7330 U per liter, the bilirubin level was 8 mg per deciliter (137 µmol per liter), and a test of the serum for hepatitis A IgM antibodies was . . . [Full Text of this Article]

The Clinical and Public Health Problems

Strategies and Evidence

Hepatitis A Vaccine

Strategies for the Use of Hepatitis A Vaccine

Immune Globulin for Passive Immunoprophylaxis

Areas of Uncertainty

Guidelines

Conclusions and Recommendations


Source Information

From the Communicable and Environmental Disease Services Section, Tennessee Department of Health (A.S.C.); and the Department of Preventive Medicine, Vanderbilt University School of Medicine (W.S.) — both in Nashville.

Address reprint requests to Dr. Schaffner at the Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, or at william.schaffner@vanderbilt.edu.


Related Letters:

Hepatitis A Vaccine
Van Herck K., Van Damme P., Rosenthal P., Craig A. S., Schaffner W.
Extract | Full Text | PDF  
N Engl J Med 2004; 350:2211-2212, May 20, 2004. Correspondence

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