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Dr. Torunn Yock (Radiation Oncology): A nine-month-old male infant was referred to this hospital for treatment of an orbital rhabdomyosarcoma. The patient had been well until the age of six months, when excessive tearing developed. Over the next two days, his right eye was noted to be puffy and red. His pediatrician made a diagnosis of conjunctivitis. Topical treatment with a combination of bacitracin and polymixin B sulfate (Polysporin) had no effect, and two days later, proptosis developed (Figure 1A). The infant was referred to an ophthalmologist for evaluation and treatment of a possible orbital infection. A computed
Pathological Discussion
Anatomical Diagnosis
Discussion of Management
Options for Chemotherapy and Potential Problems
Options for Radiation Therapy
Source Information
From the Division of Pediatric HematologyOncology, Pediatric Service (A.M.F.), and the Departments of Radiation Oncology (N.J.T.), Radiology (P.W.S.), and Pathology (B.L.H.), Massachusetts General Hospital; and the Departments of Pediatrics (A.M.F.), Radiation Oncology (N.J.T.), Radiology (P.W.S.), and Pathology (B.L.H.), Harvard Medical School.
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