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Correspondence
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Volume 350:519-520 January 29, 2004 Number 5
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Gout

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 by Terkeltaub, R. A.
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To the Editor: In discussing treatment options for gout (Oct. 23 issue),1 Terkeltaub omitted the emerging role of fenofibrate. This fibric-acid derivative is used to treat various forms of hyperlipidemia and has recently been shown to prevent the progression of coronary artery disease.2 Fenofibrate is unique among the fibrates because of its uricosuric properties and has been shown to lower serum urate levels by 19 percent in men with gout receiving established therapy with allopurinol.3 Remission of clinical episodes of gout over several years has also been reported.4

Furthermore, although this notion is controversial, high urate levels may be an . . . [Full Text of this Article]




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