The New England Journal of Medicine
e-mail icon  FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |    Advanced Search
Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe
 
Correspondence
PreviousPrevious
Volume 350:840 February 19, 2004 Number 8
NextNext

Etanercept for Crohn's Disease

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

 Sign up for free e-toc
 

This Article
-Full Text
- PDF
-PDA Full Text
-Purchase this article

Tools and Services
-Add to Personal Archive
-Add to Citation Manager
-Notify a Friend
-E-mail When Cited
-E-mail When Letters Appear

More Information
-Related Article
 by Kupper, T. S.
-PubMed Citation
To the Editor: I would like to correct an error in the Perspective by Kupper (Nov. 20 issue)1 on immunologic targets in psoriasis. Dr. Kupper indicated that etanercept (Enbrel), a tumor necrosis factor {alpha} (TNF-{alpha})–receptor fusion protein, has demonstrated efficacy in inflammatory bowel disease. In fact, in the most authoritative published experience with etanercept in the treatment of inflammatory bowel disease (a randomized, double-blind, placebo-controlled trial in patients with moderate-to-severe Crohn's disease), the drug was shown to be ineffective,2 and it does not have marketing approval for any indication in inflammatory bowel disease.


Suzanne B. Travers, M.D.
Centocor
Malvern, PA . . . [Full Text of this Article]




HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  TERMS OF USE  |  HELP  |  beta.nejm.org

Comments and questions? Please contact us.

The New England Journal of Medicine is owned, published, and copyrighted © 2009 Massachusetts Medical Society. All rights reserved.