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Previous Volume 350:924-932 February 26, 2004 Number 9 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Presentation of Case

A 48-year-old woman was evaluated in the clinic because of multiple pigmented skin lesions and a personal and family history of melanoma.

When the patient was 30 years old, a superficial spreading melanoma, 0.34 mm in thickness and Clark level II, was found on the middle lower back. A chest radiograph showed no evidence of metastatic disease. The lesion was excised with a wide margin at another hospital and did not recur. When she was 32 years old, the patient came to the Pigmented Lesion Clinic at this hospital for evaluation as a patient at high risk for melanoma. She . . . [Full Text of this Article]

Pathological Discussion

Differential Diagnosis

Inherited Disorders Associated with Pigmented Lesions

Pigmented Lesions and Cutaneous Melanoma

Familial Atypical Mole–Melanoma Syndrome

Atypical Moles

Familial Melanoma

Genetic Basis of Hereditary Melanoma

Genetic Counseling and the Role of Genetic Testing

Discussion of Management

Diagnosis

Source Information

From the Wellman Center for Photomedicine (H.T.), the Pigmented Lesion Clinic and the Department of Dermatology (H.T., A.J.S.), the Center for Cancer Risk Analysis (H.T., K.B.N.), and the Dermatopathology Unit, Department of Pathology (A.Z.), Massachusetts General Hospital; and the Departments of Dermatology (H.T., A.J.S.) and Pathology (A.Z.), Harvard Medical School.

Related Letters:

Case 7-2004: Hereditary Melanoma and Pancreatic Cancer
Koopmann J., Goggins M., Hruban R. H., Tsao H., Sober A. J., Niendorf K. B.
Extract | Full Text | PDF  
N Engl J Med 2004; 350:2623-2624, Jun 17, 2004. Correspondence

This article has been cited by other articles:

• Geller, A. C., Brooks, D. R., Colditz, G. A., Koh, H. K., Frazier, A. L. (2006). Sun Protection Practices Among Offspring of Women With Personal or Family History of Skin Cancer. Pediatrics 117: e688-e694 [Abstract] [Full Text]  
• Koopmann, J., Goggins, M., Hruban, R. H., Tsao, H., Sober, A. J., Niendorf, K. B. (2004). Case 7-2004: Hereditary Melanoma and Pancreatic Cancer. NEJM 350: 2623-2624 [Full Text]