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Clinical Implications of Basic Research
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Volume 351:1024-1026 September 2, 2004 Number 10
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No Pancreatic Endocrine Stem Cells?
Fred Levine, M.D., Ph.D., and Mark Mercola, Ph.D.

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Advances in clinical islet transplantation have raised the hope that a definitive treatment for diabetes is close. However, widespread application of islet transplantation has been limited by a shortage of donor pancreases, and emphasis has therefore been placed on devising techniques to generate insulin-producing beta cells in vitro before their transplantation into patients. A large commitment of resources from the National Institutes of Health and private foundations is directed at bringing that hope to fruition. Where, then, should we start in our effort to generate more beta cells? The two principal candidates are embryonic stem cells and various types of . . . [Full Text of this Article]


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From the Burnham Institute and the University of California, San Diego.



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