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Volume 351:1051-1053 September 9, 2004 Number 11
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Factor VIII, D-Dimer, and Thromboembolism in Children
Ulrike Nowak-Göttl, M.D., and Andrea Kosch, M.D.

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-Related Article
 by Goldenberg, N. A.
-PubMed Citation
Symptomatic venous and arterial thromboses are being diagnosed with increasing frequency in neonates, infants, and children. Because of the special properties of the hemostatic system in children, thrombotic manifestations are not rare in the pediatric population: they occur in 0.07 of every 10,000 children and account for 5.3 of every 10,000 pediatric hospital admissions and 2.4 of every 1000 admissions of newborns to intensive care units. Perhaps the lower concentrations of physiological inhibitors of the coagulation system, along with more limited fibrinolytic capacity, account for the greater risk of thromboembolic complications among neonates than among older children. The incidence of . . . [Full Text of this Article]


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From the Department of Pediatric Hematology and Oncology, University Children's Hospital, Muenster, Germany.


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