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Previous Volume 351:1120-1130 September 9, 2004 Number 11 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Presentation of Case

Newborn identical twin male infants were admitted to the neonatal intensive care unit. They were delivered at 32 weeks of gestation by a healthy 27-year-old primipara. The parents were of different ethnic backgrounds with no history of consanguinity. Prenatal screening tests revealed that the mother had group O, Rh-positive blood and was Rh-antibody–negative and immune to rubella. A test for hepatitis B surface antigen and a serologic test for syphilis were negative, as were bacterial cultures. Two days before delivery, ultrasonographic examination revealed a ring of ascites around one of the twins. An urgent delivery by cesarean section was performed . . . [Full Text of this Article]

Differential Diagnosis

Thrombocytopenia and Hepatosplenomegaly

Hemophagocytic Lymphohistiocytosis

Secondary Hemophagocytic Syndromes

Familial Hemophagocytic Lymphohistiocytosis

Diagnosis of Familial Hemophagocytic Lymphohistiocytosis

Dr. Jeffrey M. Lipton's Diagnosis

Pathological Discussion

Pathological Diagnosis

Source Information

From the Department of Pediatrics, Albert Einstein College of Medicine, Bronx, N.Y. (J.M.L.); the Division of Pediatric Hematology/Oncology and Stem Cell Transplantation, Schneider Children's Hospital, New Hyde Park, N.Y. (J.M.L.); the Department of Radiology (S.W.), the Obstetrics and Gynecology Service/Genetic Counseling (C.E.H.), and the Department of Pathology (D.R., N.L.H.), Massachusetts General Hospital; and the Departments of Radiology (S.W.), and Pathology (D.R., N.L.H.), Harvard Medical School.

This article has been cited by other articles:

• Grossman, W. J., Radhi, M., Schauer, D., Gerday, E., Grose, C., Goldman, F. D. (2005). Development of hemophagocytic lymphohistiocytosis in triplets infected with HHV-8. Blood 106: 1203-1206 [Abstract] [Full Text]