The New England Journal of Medicine
e-mail icon  FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |    Advanced Search
Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe
 
Correspondence
PreviousPrevious
Volume 351:1259-1260 September 16, 2004 Number 12
NextNext

Folate Therapy and In-Stent Restenosis

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

 Sign up for free e-toc
 

This Article
-Full Text
- PDF
-PDA Full Text
-Purchase this article

Tools and Services
-Add to Personal Archive
-Add to Citation Manager
-Notify a Friend
-E-mail When Cited
-E-mail When Letters Appear

More Information
-Related Article
by Lange, H.
-PubMed Citation
To the Editor: Lange et al. (June 24 issue)1 report an increase in the relative risk of restenosis after bare-metal stenting in patients receiving B vitamins to lower homocysteine levels. This seems to be in contrast to a previous report of a dramatic reduction in restenosis with the use of homocysteine-lowering B-vitamin treatment after coronary angioplasty.2 These two studies differ substantially (e.g., with respect to the vitamin dose, lesion length, and percutaneous coronary intervention procedures investigated). Mechanisms of restenosis in swine in response to arterial injury differ substantially between angioplasty and stenting.3 Homocysteine stimulates the proliferation of vascular smooth-muscle cells, . . . [Full Text of this Article]



HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  HELP  |  beta.nejm.org

Comments and questions? Please contact us.

The New England Journal of Medicine is owned, published, and copyrighted © 2008 Massachusetts Medical Society. All rights reserved.