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Book Review
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Volume 351:1365-1366 September 23, 2004 Number 13
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Biology and Pathology of the Oocyte: Role in Fertility and Reproductive Medicine

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Edited by Alan O. Trounson and Roger G. Gosden. 350 pp., illustrated. New York, Cambridge University Press, 2003. $90. ISBN 0-521-79958-9.

For a long time, we have been taught that the oocyte in adult mammals is virtually inactive, that it essentially remains in a resting state until the periovulatory period. Evidence that has emerged in recent years paints an entirely different picture. Aside from its contributions to the formation of an embryo, the oocyte is a master regulator of ovarian function. Far from simply waiting for ovulation to occur, the oocyte is intimately involved in the control of fertility. From the organization of follicles in newly forming ovaries to the orchestration of a complex pattern of intraovarian development, the oocyte plays . . . [Full Text of this Article]




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