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Perspective
TREATING DEPRESSION IN CHILDREN

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Volume 351:1598-1601 October 14, 2004 Number 16
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Antidepressants and Pediatric Depression — The Risk of Doing Nothing
David A. Brent, M.D.

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The editors asked two members of the Psychopharmacologic Drugs and Pediatric Advisory Committees of the Food and Drug Administration to comment on the committees' recent recommendations regarding the use of antidepressant medications in children and adolescents.

Their responses follow.


 
There is great concern that antidepressants used in children and adolescents may paradoxically increase their risk of suicidal thoughts and behavior. Is this concern valid, and if so, how should it modify our clinical approach to pediatric depression?

Twenty-five years ago, long before the introduction of selective serotonin-reuptake inhibitors (SSRIs), the adolescent suicide rate was increasing rapidly, having tripled over . . . [Full Text of this Article]


Source Information

From the Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh.


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