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Previous Volume 351:1985-1995 November 4, 2004 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The mortality from acute neurologic disorders of childhood, such as status epilepticus and stroke, is highest in infants under one year of age.^1,2 Certain forms of newborn brain injury, such as stroke, have an incidence as high as 1 in 4000 live births.³ More than 95 percent of infants who have a stroke survive to adulthood, and many have residual motor or cognitive disabilities. Stroke and other forms of brain injury have a considerable effect on surviving babies, their families, and society. Since many adult diseases have their origins in prenatal or early postnatal life,⁴ delineating the mechanisms underlying the . . . [Full Text of this Article]

Clinical Observations

Patterns of Injury

Oxidative Stress

Excitotoxicity

Inflammation

Apoptosis during Hypoxic–Ischemic Injury to the Neonatal Brain

Genetic Effects

Clinical Syndromes

Neonatal Encephalopathy

Neonatal Seizures

Neonatal Stroke

Subtle Neonatal Syndromes

Insights from Neuroimaging

Interventions

Summary

Source Information

From the Departments of Neurology and Pediatrics, University of California at San Francisco, San Francisco.

Address reprint requests to Dr. Ferriero at the Departments of Neurology and Pediatrics, University of California at San Francisco, 521 Parnassus Ave., C215, San Francisco, CA 94143-0663, or at dmf@itsa.ucsf.edu.

Related Letters:

Neonatal Brain Injury
Kruszewski S. P., Ferriero D. M.
Extract | Full Text | PDF  
N Engl J Med 2005; 352:839, Feb 24, 2005. Correspondence

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