Despite advances in the management of congestive heart failure(CHF), most patients with advanced forms die within a year afterreceiving the diagnosis. Half of all deaths from CHF are causedby ventricular tachycardia, and about 80 percent of patientswith symptomatic systolic dysfunction have ventricular tachycardia.Ischemia and myocardial scars are major determinants of therisk of ventricular tachycardia, along with some CHF therapiesthemselves for example, inotropic agents such as milrinoneand dobutamine. Other available medications include beta-blockers,agents that block the reninangiotensinaldosteronepathway, vasodilators, diuretics, and natriuretics. A new studyby Wehrens et al.1 points to . . . [Full Text of this Article]
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From the Molecular Cardiology Laboratory and Congestive Heart Failure Center, Greenberg Cardiology Division, Department of Medicine, Weill Medical College of Cornell University, New York.
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