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Volume 351:2128-2129 November 11, 2004 Number 20
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High versus Low PEEP in ARDS

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 by Levy, M. M.
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 by The National Heart, Lung, and Blood Institute ARDS Clinical Trials Network
-PubMed Citation
To the Editor: I wonder how the results of the National Heart, Lung, and Blood Institute ARDS Clinical Trials Network study (July 22 issue)1 would have looked if the recruitment maneuvers had been performed in all 276 patients who were assigned to a higher positive end-expiratory pressure (PEEP). These patients had a clinical outcome similar to that in the lower-PEEP group, although they had less favorable baseline characteristics (older age, a lower ratio of the partial pressure of arterial oxygen to the fraction of inspired oxygen [PaO2:FiO2], a higher rate of primary acute respiratory distress syndrome [ARDS] or . . . [Full Text of this Article]




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