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Volume 351:2152-2153 November 18, 2004 Number 21
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Prognosis in Follicular Lymphoma — It's in the Microenvironment
Ralf Küppers, Ph.D.

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 by Dave, S. S.
-PubMed Citation
Considerable clinical heterogeneity and wide variation in survival among patients are characteristic of many B-cell lymphomas. Prognostic markers that predict the clinical behavior of such tumors with greater accuracy than is currently possible are urgently needed to permit management decisions based on the prognosis in individual cases. Moreover, the variable course of some types of B-cell lymphomas may indicate that they are actually a mixture of distinct cancers that are not distinguished by the current classification schemes. In recent years, several large-scale studies involving microarray-based gene-expression profiling have identified novel lymphoma subtypes and improved the accuracy of predictions of outcome. . . . [Full Text of this Article]


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From the Institute for Cell Biology (Tumor Research), University of Duisburg–Essen Medical School, Essen, Germany.


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