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Previous Volume 351:2219-2227 November 18, 2004 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Presentation of Case

Dr. Amin Fazeli (Dermatology): A 68-year-old man was evaluated in this hospital by a dermatologist because of progressive thickening of the skin of the arms and legs.

The patient had had type 2 diabetes mellitus for 35 years, complicated by end-stage renal disease that required hemodialysis, diabetic neuropathy that resulted in leg pain and difficulty walking, chronic foot ulcers, and retinopathy; he was legally blind. He had coronary artery disease that had necessitated bypass grafting of four vessels, paroxysmal atrial fibrillation, and hypertension.

For the seven months before the evaluation, progressive thickening of the skin, particularly of the legs, had . . . [Full Text of this Article]

Differential Diagnosis

Lipodermatosclerosis

Nephrogenic Fibrosing Dermopathy

Differential Diagnosis of Nephrogenic Fibrosing Dermopathy

Diagnostic Procedure

Clinical Diagnosis

Dr. Samuel L. Moschella's Diagnosis

Pathological Discussion

Anatomical Diagnosis

Source Information

From the Department of Dermatology, Lahey Clinic, Burlington, Mass. (S.L.M.); the Division of Rheumatology, Department of Medicine (J.K.), the Department of Dermatology (B.T.M.), and the Division of Dermatopathology, Department of Pathology (V.L.), Massachusetts General Hospital; and the Departments of Dermatology (S.L.M., B.T.M.), Medicine (J.K.), and Pathology (V.L.), Harvard Medical School.

Related Letters:

Case 35-2004: Nephrogenic Fibrosing Dermopathy
Taylor R. A., Levine J. M., Jimenez S. A., Cowper S. E., Bucala R., LeBoit P. E., Moschella S. L., Kay J., Liu V.
Extract | Full Text | PDF  
N Engl J Med 2005; 352:1723-1724, Apr 21, 2005. Correspondence

This article has been cited by other articles:

• Kay, J (2008). Nephrogenic systemic fibrosis: a gadolinium-associated fibrosing disorder in patients with renal dysfunction. Ann Rheum Dis 67: iii66-iii69 [Abstract] [Full Text]  
• KAY, J. (2008). Gadolinium and nephrogenic systemic fibrosis: The evidence of things not seen. Cleveland Clinic Journal of Medicine 75: 112-117 [Full Text]  
• Grobner, T. (2006). Gadolinium - a specific trigger for the development of nephrogenic fibrosing dermopathy and nephrogenic systemic fibrosis?. Nephrol Dial Transplant 21: 1104-1108 [Full Text]  
• Taylor, R. A., Levine, J. M., Jimenez, S. A., Cowper, S. E., Bucala, R., LeBoit, P. E., Moschella, S. L., Kay, J., Liu, V. (2005). Case 35-2004: Nephrogenic Fibrosing Dermopathy. NEJM 352: 1723-1724 [Full Text]