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A 23-day-old male infant was admitted to this hospital because of difficulty feeding and failure to thrive.
His weight at birth was 2580 g; he was 45 cm long, the product of an uncomplicated, full-term pregnancy, and born by spontaneous vaginal delivery at another hospital to a 23-year-old woman (gravida 2, para 1). An obstetrical ultrasonographic evaluation at 21 weeks' gestation had shown no abnormalities. At delivery, the amniotic fluid was stained with meconium and there was a nuchal cord. Apgar scores were 2 at one minute and 7 at five minutes. He was briefly intubated and suctioned, and continuous
Differential Diagnosis
Definition and Causes of Failure to Thrive
Prenatal Causes of Failure to Thrive
Postnatal Causes of Failure to Thrive
The Differential Diagnosis in This Case
Pathological Discussion
Discussion of Management
Final Diagnosis
Source Information
From the Departments of Medical Genetics (J.M.S.) and Pediatric Surgery (P.K.D.), Massachusetts General Hospital; the Department of Pathology, Brigham and Women's Hospital (N.T.L.); and the Departments of Pediatrics (J.M.S.), Pathology (N.T.L.), and Surgery (P.K.D.), Harvard Medical School all in Boston.
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