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Editorial
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Volume 351:2330-2332 November 25, 2004 Number 22
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Intradermal Influenza Vaccination — Can Less Be More?
John R. La Montagne, Ph.D., and Anthony S. Fauci, M.D.

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-Related Article
 by Belshe, R. B.
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 by Kenney, R. T.
-PubMed Citation
The current shortfall in anticipated doses of vaccine for the upcoming influenza season1 makes the reports by Belshe et al.2 and Kenney et al.3 in this issue of the Journal particularly timely. These studies raise the possibility of using alternative routes of immunization (e.g., intradermal, as opposed to intramuscular, administration) with smaller doses of vaccine as a means of "stretching" available doses of influenza vaccine in times of shortages. In addition, the studies indirectly raise provocative issues regarding the potential effect of these alternative routes of immunization in targeting specialized cells of the immune system to enhance the immunogenicity of . . . [Full Text of this Article]


Source Information

This article was published at www.nejm.org on November 4, 2004.

From the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.

John R. La Montagne, Ph.D., is deceased.


Related Letters:

Intradermal Vaccination against Influenza
Weller T. H., Kilbourne E. D., Manian F. A., Belshe R. B., Treanor J., Dubin G., Glenn G. M., Kenney R. T.
Extract | Full Text | PDF  
N Engl J Med 2005; 352:1044-1046, Mar 10, 2005. Correspondence

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