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Volume 351:2448-2450 December 2, 2004 Number 23
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Hyperkalemia after the Publication of RALES

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 by Juurlink, D. N.
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To the Editor: The data presented by Juurlink et al. (Aug. 5 issue)1 regarding hyperkalemia that was attributed to spironolactone do not justify the conclusion that the rate of admission for hyperkalemia increased. The authors identified "all hospital admissions involving a diagnosis of hyperkalemia," and their database included "up to 16 diagnoses for each admission." They did not review individual records. Therefore, they could not distinguish admissions for hyperkalemia from admissions for other diagnoses that involved hyperkalemia. They should have excluded patients with other primary indications for admission before concluding that the rate of admissions for hyperkalemia increased.2 Since no . . . [Full Text of this Article]


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