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Correspondence
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Volume 351:2456-2457 December 2, 2004 Number 23
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Follow-up 26 Years after Treatment for Acute Myelogenous Leukemia

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To the Editor: In 1979, we reported the results of treating 19 patients who had acute myelogenous leukemia in first remission with intensive chemotherapy, radiation therapy, and transplantation of allogeneic marrow from HLA-identical siblings between March 1976 and March 1978.1 These patients had been treated with cyclophosphamide, total-body irradiation (one exposure of 920 cGy), and prophylaxis with methotrexate for graft-versus-host disease (GVHD). Five patients died from interstitial pneumonia within six months of transplantation, one patient relapsed and died at one year, and one died at one year with septicemia complicating chronic GVHD. Four patients were alive with minimal chronic GVHD, . . . [Full Text of this Article]


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