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A correction has been published: N Engl J Med 2005;352(1):104.

Review Article
Medical Progress
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Volume 351:2519-2529 December 9, 2004 Number 24
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Cancer of the Ovary
Stephen A. Cannistra, M.D.

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Epithelial cancer of the ovary is a relatively uncommon gynecologic cancer in the United States, with approximately 25,580 new cases and 16,090 deaths anticipated in 2004.1 Most patients present with advanced disease, which is managed with surgical resection followed by platinum-based chemotherapy. During the past decade, advances in chemotherapy have resulted in improved survival and in more effective treatment of relapsed disease. In addition, a better understanding of genetic risk factors has permitted a tailored approach to preventive strategies, such as bilateral salpingo-oophorectomy in selected women. This review describes the clinical features of epithelial ovarian cancer, with an emphasis on . . . [Full Text of this Article]

Epidemiology and Risk Factors

Familial Syndromes

Prophylactic Treatment for Women with Germ-Line Mutations in BRCA1 or BRCA2

Clinical Presentation

Surgery

Postoperative Chemotherapy

Early-Stage Disease

Advanced Disease

Management of Recurrent Disease

Prospects for a Brighter Future


Source Information

From the Program of Gynecologic Medical Oncology, Beth Israel Deaconess Medical Center, Boston.

Address reprint requests to Dr. Cannistra at the Program of Gynecologic Medical Oncology, Beth Israel Deaconess Medical Center, 330 Brookline Ave., Boston, MA 02215, or at scannist@bidmc.harvard.edu.


Related Letters:

Cancer of the Ovary
Matulonis U., Abrahm J. L., Liu C.-M., Cannistra S. A.
Extract | Full Text | PDF  
N Engl J Med 2005; 352:1268-1269, Mar 24, 2005. Correspondence

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