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Volume 351:2554-2556 December 9, 2004 Number 24
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Chronic Vulvovaginal Candidiasis

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 by Eschenbach, D. A.
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 by Sobel, J. D.
-PubMed Citation
To the Editor: The results of the study of maintenance fluconazole therapy for recurrent vulvovaginal candidiasis by Sobel et al. (Aug. 26 issue)1 are misleading. A better assessment of the effect of weekly maintenance fluconazole therapy would be obtained by comparing the proportions of women who were free of disease at a given time after the most recent dose of fluconazole. This study shows that women who receive weekly therapy with fluconazole for six months have a 57 percent chance of a recurrence within six months after the last dose of fluconazole, whereas women who receive one dose of fluconazole . . . [Full Text of this Article]




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