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Case Records of the Massachusetts General Hospital
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Volume 351:2637-2645 December 16, 2004 Number 25
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Case 38-2004 — A 40-Year-Old Man with a Large Tumor of the Skull
Paul G. Richardson, M.D., Ara Kassarjian, M.D., and Wen Jing, M.D.

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Presentation of Case

Dr. Ronald Takvorian (Hematology–Oncology): A 40-year-old man was admitted to this hospital because of a mass of the skull. The patient had been in his usual state of good health until two months before admission, when he noticed a firm, walnut-sized, painless mass on the top of his head. It enlarged slightly during the next couple of months, and he saw his primary care physician. Computed tomographic (CT) and magnetic resonance imaging (MRI) scans showed an intracranial lesion thought to be a meningioma; the patient was referred to a neurosurgeon at this hospital.

The patient had been told previously that . . . [Full Text of this Article]

Differential Diagnosis

Pathological Discussion

Discussion of Management

Initial Therapy for Plasma-Cell Myeloma

            Combination Chemotherapy

            Thalidomide

            Bortezomib

Stem-Cell Transplantation

Anatomical Diagnosis


Source Information

From the Jerome Lipper Multiple Myeloma Center, Division of Hematologic Oncology, Department of Medicine, Brigham and Women's Hospital and the Dana–Farber Cancer Institute (P.G.R.); the Departments of Radiology (A.K.) and Pathology (W.J.), Massachusetts General Hospital; and the Departments of Medicine (P.G.R.), Radiology (A.K.), and Pathology (W.J.), Harvard Medical School.


Related Letters:

Case 38-2004: A Large Tumor of the Skull
Badros A. Z., Richardson P. G., Kassarjian A., Jing W.
Extract | Full Text | PDF  
N Engl J Med 2005; 352:1610, Apr 14, 2005. Correspondence

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