FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 351:2881-2883 December 30, 2004 Number 27 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by Schlossmacher, M. G. PubMed Citation

To the Editor: In reviewing the differential diagnosis in the case of a woman with disturbances in gait, cognition, and autonomic function, Schlossmacher provides a scholarly discussion of multiple-system atrophy (Aug. 26 issue),¹ but he errs by including pure autonomic failure as one of four syndromes subsumed under the diagnosis of multiple-system atrophy.

Pure autonomic failure is a distinct and separate clinical entity that affects postganglionic neurons. Autonomic impairment is the principal manifestation; orthostatic hypotension, bladder incontinence, and impotence in men are the major signs.² Pure autonomic failure differs importantly from multiple-system atrophy in its lack of any sensory, cerebellar, . . . [Full Text of this Article]

HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  HELP  |  beta.nejm.org Comments and questions? Please contact us. The New England Journal of Medicine is owned, published, and copyrighted © 2008 Massachusetts Medical Society. All rights reserved.