Those with sufficiently long memories must be somewhat bemusedby the successive controversies surrounding the treatment ofprimary hypothyroidism, a condition viewed by many as simple,satisfying to manage, and very much within the purview of theprimary care physician, rather than the specialist. The developmentof sensitive assays for measuring thyrotropin has led to a reductionin levothyroxine doses; in most patients, a dose of only 100to 125 µg daily restores serum thyrotropin levels to thereference range, thereby satisfying the 1990 recommendationsof the American Thyroid Association,1 which have since beenreinforced.2 There is no consensus, however, . . . [Full Text of this Article]
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From the Royal Infirmary, Edinburgh, Scotland.
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