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A correction has been published: N Engl J Med 2004;351(17):1803.

Review Article
Current Concepts
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Volume 351:370-378 July 22, 2004 Number 4
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Flavivirus Encephalitis
Tom Solomon, M.D., Ph.D.

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 by Handy, R.
-PubMed Citation
During the summers of 2002 and 2003, North America was affected by its largest-ever outbreaks of arboviral encephalitis. West Nile virus caused 2942 cases of meningitis or encephalitis in 2002, with 276 deaths, and 2866 cases in 2003, with 246 deaths.1,2 West Nile virus, which in the United States was first detected in New York in 1999, is one of several mosquito-borne neurotropic members of the Japanese encephalitis (JE) serogroup of the genus flavivirus, family Flaviviridae, that cause similar disease patterns across the globe (Figure 1 and Table 1). These include St. Louis encephalitis virus in the United . . . [Full Text of this Article]

Ecology and Epidemiology

Pathogenesis

Clinical Features

Seizures

Poliomyelitis-Like Paralysis

Parkinsonian Movement Disorders

Diagnosis and Treatment

Future Prospects


Source Information

From the Departments of Neurological Science and Medical Microbiology, University of Liverpool, Liverpool, United Kingdom.

Address reprint requests to Dr. Solomon at the Department of Neurological Science, University of Liverpool, Walton Centre for Neurology and Neurosurgery, Liverpool L9 7LJ, United Kingdom, or at tsolomon@liv.ac.uk.


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