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Previous Volume 351:832-834 August 19, 2004 Number 8 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: We agree with Horsburgh (May 13 issue)¹ that the lifetime risk of active tuberculosis is helpful in deciding whether to treat latent tuberculosis infection.^2,3 Attention to three problems addressed years ago^2,3,4 would improve Horsburgh's analysis: the rate at which the risk of active tuberculosis falls with time^2,3 was underestimated, discounting⁵ was ignored, and the risk of treatment^2,3,4 was not incorporated into the analysis. A corrected analysis would reveal a substantially lower lifetime risk of active tuberculosis, especially among young persons and persons in risk groups with the highest rates of active tuberculosis, with the possible exception of . . . [Full Text of this Article]

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