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Previous Volume 352:98-100 January 6, 2005 Number 1 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Cardiac troponins are preferred markers of tissue injury in acute coronary syndromes. Their specificity and the fact that only very minute amounts or none are normally found in the circulation provide high clinical sensitivity and specificity even when cardiac lesions are small. The importance of cardiac troponins in identifying high-risk patients to receive active intervention is widely recognized.¹

Troponins present substantial challenges with respect to immunoassays, however. They occur as various complexes or fragments and show other forms of heterogeneity.² In addition, we recently reported³ that serum from many patients contains an interfering factor that prevents the . . . [Full Text of this Article]

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