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Previous Volume 352:1051-1052 March 10, 2005 Number 10 Next

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(Scientific and Technical Publication No. 596.) Edited by Ciro A. de Quadros. 398 pp., illustrated. Washington, D.C., Pan American Health Organization, 2004. $62. ISBN 92-75-11596-6.

From the first to the last chapter, from AIDS to zoster, this book is a gem. It covers the field of vaccines from basic to clinical science and on to public health and the implementation of vaccines, focusing on the successes but not avoiding the areas that still pose problems. As a public health tool, vaccines are the most cost-effective intervention you can buy. But most of the low-hanging fruit has been picked, and the vaccines yet to be developed pose challenges for basic science (e.g., vaccines for the human immunodeficiency virus [HIV] and malaria), for clinical science (respiratory syncytial . . . [Full Text of this Article]

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