This Journal feature begins with a case vignette highlightinga common clinical problem. Evidence supporting various strategiesis then presented, followed by a review of formal guidelines,when they exist. The article ends with the authors' clinicalrecommendations.
Six weeks ago, a 45-year-old woman noticed a scratchy feelingin her throat that has now progressed to more than 20 episodesof severe, spasmodic coughing per day. Her coughing spells areworse at night and are sometimes associated with gagging andvomiting. Her adolescent son and several of his friends, whoreceived all of their childhood immunizations on schedule, hadsimilar . . . [Full Text of this Article]
The Clinical Problem
Clinical Presentation and Complications
Epidemiology, Incidence, and Burden of Disease
Strategies and Evidence
Diagnostic Methods
Treatment
Prophylaxis after Exposure
Prevention
Areas of Uncertainty
Guidelines
Conclusions and Recommendations
Source Information
From the Division of Infectious Diseases and International Health, Departments of Medicine and Pharmacology, University of Virginia School of Medicine, Charlottesville (E.L.H.); and the Division of Pediatric Infectious Diseases, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville (K.M.E.).
Address reprint requests to Dr. Hewlett at P.O. Box 800419, University of Virginia School of Medicine, Charlottesville, VA 22908, or at eh2v@virginia.edu.
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